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  • Fenilpropanolamina

Ações terapêuticas.

Descongestionante nasal.

Propriedades.

Amina simpatomimética que provoca vasoconstricção da mucosa do trato respiratório por atuar sobre os receptores alfa adrenérgicos, o que resulta em uma redução do edema e da inflamação rino-sinusal. A fenilpropanolamina possui ação anorexígena e estimulante do SNC. Produz aumento da freqüência cardíaca, da contractilidade do débito cardíaco e da excitabilidade do músculo cardíaco; em pacientes portadores de elevada sensibilidade aos simpatomiméticos podem ocorrer exacerbação do efeito vasopressor, taquicardia e hipertensão arterial. Absorve-se bem no trato gastrintestinal; metaboliza-se no fígado e sua vida média é de 3 a 4 horas. Elimina-se por via renal.

Indicações.

Rinopatias alérgicas, rinites, sinusites, resfriado comum, patologias inflamatórias e congestivas do trato respiratório superior.

Posologia.

Utiliza-se associado com outros descongestionantes e/ou com anti-histamínicos. Crianças (1 a 6 meses): 3mg a 6mg a cada 4-6 horas; 7 meses a 2 anos: 6mg a 12mg a cada 4-6 horas; 2 a 4 anos: 9mg a 18mg a cada 4-6 horas; 4 a 12 anos: 12,5mg a 25mg a cada 4-6 horas. Adultos e crianças maiores de 12 anos: 12,5mg a 50mg a cada 4-6 horas.

Superdosagem.

Tratamento sintomático.

Reações adversas.

Taquicardia, extra-sistolia, hipertensão arterial, tremor, nervosismo, cefaléia. Alterações no estado de ânimo ou mental. Hemorragias ou hematomas não-habituais. Dor de garganta e febre.

Precauções.

Utilizar com precaução em pacientes com: diabetes mellitus, patologias cardiovasculares, glaucoma de ângulo fechado (ou pré-dispostos), hipertensão arterial severa (precipitação da crise hipertensiva), hipertireoidismo (aumento da taquicardia) e hipertrofia prostática assintomática (retenção urinária). O risco/benefício deve ser avaliado durante a gravidez e o aleitamento. Crianças podem apresentar maior sensibilidade aos efeitos vasoconstritores da fenilpropanolamina.

Interações.

Anestésicos voláteis. Glicosídeos digitálicos (previamente à anestesia). Bloqueadores beta-adrenérgicos, hipertensão e bradicardia excessiva. Estimulantes do SNC (efeitos aditivos) Doxapram (sinergismo vasopressor). Guanadrel e guanetidina (hipertensão e arritmias cardíacas). Alcalóides de Rauwolfia.

Contra-indicações.

Hipersensibilidade às aminas simpatomiméticas.

Fenilpropanolamina

  • Modelo: IMPORTADO - PARAGUAI
  • Disponibilidade: Em estoque
  • R$99,00


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